View details for DOI 10.1073/pnas.2021726118. On the basis of a review of the literature, commercial information, and structured expert interviews, we performed a sensitivity analysis to determine the incremental economic benefit of using modern NEMT. Cox proportional hazard models quantified the risk of MMD and PMMD in PA vs HE stratified by baseline fatigue adjusted for covariates.RESULTS: Among those with higher baseline fatigue, PA participants had a 29% and 40% lower risk of MMD and PMMD, respectively, over the trial compared with HE (hazard ratio [HR] for MMD=.71; 95% confidence interval [CI] =.57-.90; P=.004) and PMMD (HR=.60; 95% CI=.44-.82; P=.001). View Details. . View details for DOI 10.1016/j.amerpe.2007.04.031, View details for Web of Science ID 000249452700008, View details for PubMedCentralID PMC1995005, President's Award for Career Achievement, International Society for Quality of Life Research (2004), Distinguished Career Service Award, Society of Behavioral Medicine (2005), Elected Member, National Academy of Medicine (2005), Astra ZenecaPrize for Best Original Research Article, Astra Zeneca (2006), Outstanding Research Mentor Award, Society of Behavioral Medicine (2006), List of Most Cited Authors, Institute for Scientific Information (2006-present), C Tracy Orleans Award, Society of Behavioral Medicine (2011), Health Policy Scientist of the Year, American Sociological Association (2012), Presidential Citation for Outstanding Contribution, American Psychological Association (2012), Nathan Perry Award for Distinguished Service, Society for Health Psychology (2017), Elizabeth Fries Award, CDC Foundation (2020), President, American Psychological Association, Division of Health Psychology (1991 - 1992), President, International Society for Quality of Life Research (1995 - 1996), President, Society of Behavioral Medicine (1996 - 1997), Chair, Behavioral Science Council, American Thoracic Society (2001 - 2003), President, Academy of Behavioral Medicine Research (2002 - 2003), Co-Chair, BSE Subcommittee, White House National Committee on Science and Technology Policy (2011 - 2015), Member, National Committee for Vital and Health Statistics, National Center for Health Statistics (2011 - 2015), Member, Social, Behavioral, and Economic Sciences Advisory Committee, National Science Foundation (2011 - 2015), Department: Med/Primary Care and Population Health. In addition, consistent indexing in databases, such as MEDLINE, would allow for better matching of records and publications, leading to increased utility of these searches for systematic review projects. Bann, D., Hire, D., Manini, T., Cooper, R., Botoseneanu, A., McDermott, M. M., Pahor, M., Glynn, N. W., Fielding, R., King, A. C., Church, T., Ambrosius, W. T., Gill, T. Association of objectively measured physical activity with cardiovascular risk in mobility-limited older adults. A., Gill, T. M., Marsh, A. P., Hsu, F., Yaghjyan, L., Woods, A. J., Glynn, N. W., King, A. C., Newton, R. L., Fielding, R. A., Pahor, M., Manini, T. M., Lifestyles Intervention and Independence for Elders Study Investigators. His 20 books and over 560 articles or chapters have been cited more than 55,000 times (H-index>100) and the ISI includes him in the listing of the most cited authors in his field (defined as above the 99.5th percentile). Consistent with prior research, the AS incidence rate was greater in the White population than the Black population (aOR = 1.39, 95% CI 1.01 - 1.66, p = 0.04).CONCLUSION: In this study population, the incidence of AS was similar for the sexes. People Projects Discussions . Looking for books by Robert M. Kaplan? B., Lifestyle Interventions and Independence for Elders Study Group, Pahor, M., Guralnik, J. M., Anton, S. D., Buford, T. W., Leeuwenburgh, C., Nayfield, S. G., Manini, T. M., Caudle, C., Crump, L., Holmes, L., Lee, J., Lu, C., Miller, M. E., Espeland, M. A., Ambrosius, W. T., Applegate, W., Beavers, D. P., Byington, R. P., Cook, D., Furberg, C. D., Harvin, L. N., Henkin, L., Hepler, J., Hsu, F., Joyce, K., Lovato, L., Pierce, J., Roberson, W., Robertson, J., Rushing, J., Rushing, S., Stowe, C. L., Walkup, M. P., Hire, D., Rejeski, W. J., Katula, J. In two of these eight tests, a -LR (0.25 and 0.004) excluded the induction of 'Perceived Safety'.Communication of test results caused perceived anxiety but not perceived safety in 80% of the investigated tests. The outcome was respondents' reported likelihood of receiving a vaccine for the coronavirus. We investigated whether information in ClinicalTrials.gov would impact the conclusions of five ongoing systematic reviews.We considered five reviews that included 495 studies total. A 'safety loop' model postulates risk-related decisions are not based on objective and measurable risks but on the subjective perception of those risks. Identifying modifiable determinants of fat mass and muscle strength in older adults is important given their impact on physical functioning and health. Robert M. Kaplan, Ph.D. is a Distinguished Professor of the Health Services at UCLA and Distinguished Professor of Medicine at the UCLA David Geffen School of Medicine. Phone Numbers: 419-194-1606. Three articles address (1) standardizing methods for conducting cost-effectiveness and cost-utility analyses, (2) providing examples to illustrate progress in applying these methods to evaluate interventions delivered in whole or in part in clinical settings, and (3) providing nonclinical intervention examples selected to highlight the challenges and opportunities for evaluating the cost-effectiveness of interventions in more diverse settings. However, variability exists in seniors' responsiveness to training. A preliminary cost/effectiveness analysis gauged the cost/disability avoided to be $28,206. Robert M. Kaplan has served as Chief Science Officer at the US Agency for Health Care Research and Quality (AHRQ) and Associate Director of the National Institutes of Health, where he led the behavioral and social sciences programs. The physical activity and exercise intervention resulted in statistically significantly lower decline in eGFRCysC over 2 years compared with the health education arm (mean difference, 0.96 mL/min/1.73 m2; 95% CI, 0.02-1.91 mL/min/1.73 m2) and lower odds of rapid eGFRCysC decline (odds ratio, 0.79; 95% CI, 0.65-0.97).Conclusions and Relevance: Results of this ancillary analysis of a randomized clinical trial showed that when compared with health education, a physical activity and exercise intervention slowed the rate of decline in eGFRCysC among community-dwelling sedentary older adults. Conjoint analysis may be a more robust approach to preference measurement for men at risk for prostate cancer. Porzsolt, F., Wiedemann, F., Phlippen, M., Weiss, C., Weiss, M., Schmaling, K., Kaplan, R. M. Efficacy and effectiveness studies of depression are not well-differentiated in the literature: a systematic review. Dismiss. View details for DOI 10.1001/jama.2014.5616, View details for Web of Science ID 000337301500019. Lastly, the IBMT group had stronger brain connectivity between the dorsal anterior cingulate cortex (dACC) and the striatum at resting state, as well as greater volume of gray matter in the striatum. Multivariate linear regression modeling was used to examine covariates of health-related quality of life over time in 2017.RESULTS: The sample had an overall mean Quality of Well-Being score of 0.613. C-terminal Agrin Fragment (CAF) has been proposed as a potential circulating biomarker for predicting changes in physical function among older adults. View details for DOI 10.1136/bmjebm-2020-111641. Of the 173 total ClinicalTrials.gov records identified across the five projects, between 11 and 43% did not have an associated publication. Published online ahead of print January 24, 2019: e1-e3. B., Studenski, S. A., Goodpaster, B. H., Lopez, O., Nadkarni, N. K., Ives, D. G., Newman, M. A., Grove, G., Williams, K., Bonk, J. T., Rush, J., Kost, P., Vincent, P., Gerger, A., Romeo, J. R., Monheim, L. C., Kritchevsky, S. B., Marsh, A. P., Brinkley, T. E., Demons, J. S., Sink, K. M., Kennedy, K., Shertzer-Skinner, R., Wrights, A., Fries, R., Barr, D., Gill, T. M., Axtell, R. S., Kashaf, S. S., de Rekeneire, N., McGloin, J. M., Mautner, R., Huie-White, S. M., Bianco, L., Zocher, J., Wu, K. C., Shepard, D. M., Fennelly, B., Castro, R., Halpin, S., Brennan, M., Barnett, T., Iannone, L. P., Zenoni, M. A., Bugaj, J. Behavioral interventions often use measures that are not generally applied in other areas of health outcomes research. Professor Robert S. Kaplan and Senior Researcher Ricardo Reisen de Pinho of the Latin America Research Center prepared this case with guidance and assistance from Professor Krishna Palepu. View details for DOI 10.1016/j.jamda.2015.03.010, View details for Web of Science ID 000358423400010, View details for PubMedCentralID PMC4516564. More than Medicine Robert M. Kaplan | Harvard University Press B., Kritchevsky, S. B., Myers, V., Manini, T. M., Pahor, M., LIFE Study Grp. His Randomized controlled trial research integrates issues from Clinical trial, Intensive care medicine, Pharmacotherapy, Evidence-based practice and Social support. Health care has modest effects on the extension of US life expectancy, while behavioral and social determinants may have larger effects. Rare Classic Car Preview. Forensic psychiatrist and historian Robert M. Kaplan is of the opinion the coronavirus pandemic will not last that much longer. However, a significant interaction was observed between sex and count frequency (P=0.036) for those without CVD, as counts per minute was related to HCHD risk in women (=-0.94, -1.48 to -0.41; P<0.001) but not in men (=-0.14, -0.59 to 0.88; P=0.704).Daily time spent being sedentary is positively associated with predicted 10-year HCHD risk among mobility-limited older adults. South African Medical Journal March 2001, 90-3;216-217.] He is a past President of several organizations, including the American Psychological Association Division of Health Psychology, Section J of the American Association for the Advancement of Science (Pacific), the International Society for Quality of Life Research, the Society for Behavioral Medicine, and the Academy of Behavioral Medicine Research. View details for PubMedCentralID PMC4772786. Age-stratified recursive partitioning methods were applied to identify distinct subgroups with varying obesity prevalence.Among participants aged 70-78 years, four distinct subgroups, defined by combinations of perceived environment and race-ethnicity variables, were identified. These findings suggest mobility benefit from such a program in vulnerable older adults.clinicaltrials.gov Identifier: NCT01072500. Mr. Kaplan holds degrees from Cape Town University and Columbia University. Groessl, E. J., Kaplan, R. M., Castro Sweet, C. M., Church, T., Espeland, M. A., Gill, T. M., Glynn, N. W., King, A. C., Kritchevsky, S., Manini, T., McDermott, M. M., Reid, K. F., Rushing, J., Pahor, M. Cost-effectiveness of the LIFE Physical Activity Intervention for Older Adults at Increased Risk for Mobility Disability. Secondary analyses classified intervention participants into two subgroups, (1) individual therapy only or (2) group training (i.e., coping skills training) plus individual therapy, to determine whether medical outcomes differed in participants who received the combination of group training and individual therapy compared to participants who received individual therapy only or usual care.Secondary analyses of 1243 usual care, 781 individual therapy only, and 356 group plus individual therapy myocardial infarction (MI) patients were performed. These data illustrate that it is not feasible to have a single exercise prescription for older adults with compromised function. Robert M. Kaplan is a faculty member at Stanford Medicine's Clinical Excellence Research Center and a distinguished professor emeritus at the UCLA Fielding School of Public Health. However, more research is necessary to conclusively rule out medical care as a mediator between education and health. The University of Wollongong expert, who is well known for his work studying the Spanish Flu and Encephalitis lethargica epidemics, fears another epidemic is just around the corner. The absence of interaction effects suggests that respondents consider the side effects and benefits independently. These null results were accompanied by suggestive evidence that the physical activity program may reduce the rate of fall related fractures and hospital admissions in men.Trial registration ClinicalsTrials.gov NCT01072500. Bondoc, I., Cochrane, S. K., Church, T. S., Dahinden, P., Hettwer, S., Hsu, F., Stafford, R. S., Pahor, M., Buford, T. W. Effect of a 24-Month Physical Activity Intervention vs Health Education on Cognitive Outcomes in Sedentary Older Adults The LIFE Randomized Trial. 424 older adults at risk for mobility disability were randomly assigned to either condition. Dismiss. South Africa . Robert Kaplan Finance Director at Pensana Plc City of Johannesburg, Gauteng, South Africa 364 followers 352 connections Join to view profile Pensana Plc University of the Witwatersrand. He graduated from Chicago College of Osteopathic Medicine in 1973. For those with lower baseline fatigue, no group differences in MMD (P=.36) or PMMD (P=.82) were found. Porzsolt, F., Pfuhl, G., Kaplan, R. M., Eisemann, M. The terminology conflict on efficacy and effectiveness in healthcare. Schaumburg, IL 60194. 416 (57.4%) of the studies posted some results. Cognitive function was reassessed 24 months later (interviewer-administered) and 18 or 30 months later (computer-administered) and central adjudication was used to classify individuals as having mild cognitive impairment, probable dementia, or neither.Lower ABI had a modest independent association with poorer cognitive functioning at baseline (partial r= 0.09; P < .001). Physical activity was measured by step count and minutes of moderate-intensity activity using accelerometers.Main Outcomes and Measures: The primary outcome was change in eGFRCysC. In the case of COVID-19 tests may induce more perceived anxiety than safety. With support from the Society for Health Psychology, the National Cancer Institute (NCI), and the Office for Behavioral and Social Sciences Research (OBSSR) at the National Institutes of Health, two working group meetings were held to consider the use of well-established cost-effectiveness methodologies for the evaluation of behavioral and public health interventions. Several studies have shown that regular physical activity improves functional limitations and intermediate functional outcomes, but definitive evidence showing that major mobility disability can be prevented is lacking. Updated: October 4, 2011 . Rejeski, W. J., Rushing, J., Guralnik, J. M., Ip, E. H., King, A. C., Manini, T. M., Marsh, A. P., McDermott, M. M., Fielding, R. A., Newman, A. These mixed results might reflect heterogeneity in response to physical activity, with some subgroups of individuals responding positively, but not others.1) To examine the impact of genetic variation and sex on changes in depressive symptoms in older adults after a physical activity (PA) intervention, and 2) to determine if PA differentially improves particular symptom dimensions of depression.Randomized controlled trial.Four field centers (Cooper Institute, Stanford University, University of Pittsburgh, and Wake Forest University).396 community-dwelling adults aged 70-89 years who participated in the Lifestyle Interventions and Independence for Elders Pilot Study (LIFE-P).12-month PA intervention compared to an education control.Polymorphisms in the serotonin transporter (5-HTT), brain-derived neurotrophic factor (BDNF), and apolipoprotein E (APOE) genes; 12-month change in the Center for Epidemiologic Studies Depression Scale total score, as well as scores on the depressed affect, somatic symptoms, and lack of positive affect subscales.Men randomized to the PA arm showed the greatest decreases in somatic symptoms, with a preferential benefit in male carriers of the BDNF Met allele. Covid-19 pandemic lessons: uncritical communication of test results can induce more harm than benefit and raises questions on standardized quality criteria for communication and liability. . To explore vaccine acceptance decisions, we conducted a national survey of 1,000 people from all US states in August of 2020 and a replication in December of 2020. B., Rejeski, W., Guralnik, J. M., Pahor, M., Fielding, R. A., LIFE Study Investigators. Limited evidence suggests that physical activity may help prevent mobility disability; however, there are no definitive clinical trials examining whether physical activity prevents or delays mobility disability.To test the hypothesis that a long-term structured physical activity program is more effective than a health education program (also referred to as a successful aging program) in reducing the risk of major mobility disability.The Lifestyle Interventions and Independence for Elders (LIFE) study was a multicenter, randomized trial that enrolled participants between February 2010 and December 2011, who participated for an average of 2.6 years. Prof Robert Kaplan - Business Results Group Two different functions (confirmation and exclusion) of both perceptions (Perceived Anxiety and Safety) can be quantified with those calculations.The analysis of six published tests and of one incompletely reported test on COVID-19 polymerase chain reactions (completed by four assumptions on high and low sensitivities and specificities) demonstrated that none of these tests induces 'Perceived Safety'. A Conversation With Robert Kaplan - Council on Foreign Relations These include the EQ-5D, the Health Utilities Index (HUI), the self-administered Quality of Well-being Scale (QWB-SA), and the Health and Activities Limitation Index (HALex). Robert S. Kaplan - Faculty & Research - Harvard Business School Psychosocial treatment followed MI, and for participants with severe or unremitting depression, was supplemented with a selective serotonin reuptake inhibitor. These results are consistent with the hypothesis that replacing sedentary activities with light intensity activities could lead to lower BMI levels and obesity prevalence among the population of older adults. Rather than reading a good book with a cup of coffee in the afternoon, instead they cope with some infectious bugs inside their desktop computer. Rejeski, W. J., Axtell, R., Fielding, R., Katula, J., King, A. C., Manini, T. M., Marsh, A. P., Pahor, M., Rego, A., Tudor-Locke, C., Newman, M., Walkup, M. P., Miller, M. E. Determinants of Racial/Ethnic Disparities in Incidence of Diabetes in Postmenopausal Women in the U.S. America's medical system is . A., Bailey, C., Charpentier, P., Hawthorne-Jones, G., Mignosa, B., Lewis, L., Williamson, J., Hendrie, H. C., Rapp, S. R., Verghese, J., Woolard, N., Espeland, M., Jennings, J., Wilson, V. K., Pepine, C. J., Ariet, M., Handberg, E., Deluca, D., Hill, J., Szady, A., Chupp, G. L., Flynn, G. M., Hankinson, J. L., Fragoso, C., Groessl, E. J., Kaplan, R. M., LIFE Study Grp. The mental component summary (MCS) score of the 12-item Short Form (SF-12) was used as a measure of mental health status. Multivariate regression analysis suggested that adjustment for age, race, poverty status and marital status explained part, but not nearly all, of the relationship between education and health. View details for Web of Science ID 000391236900011. NIH Director Announces Appointment of Robert Kaplan as Associate 2019: Our news : May - July - UCT MEDICAL SCHOOL CLASS 1973 Participants were sedentary adults aged 70 to 89 years who were at risk for mobility disability but able to walk 400 m.A structured, moderate-intensity physical activity program (n=818) that included walking, resistance training, and flexibility exercises or a health education program (n=817) of educational workshops and upper-extremity stretching.Prespecified secondary outcomes of the LIFE study included cognitive function measured by the Digit Symbol Coding (DSC) task subtest of the Wechsler Adult Intelligence Scale (score range: 0-133; higher scores indicate better function) and the revised Hopkins Verbal Learning Test (HVLT-R; 12-item word list recall task) assessed in 1476 participants (90.3%). We examined the costs of a physical activity (PA) and an educational comparison intervention. Robert M Kaplan. Download free pdf or Buy Books For the next TRICARE contracts which will begin in 2023, the DoD asked its health-focused federal advisory committee, the Defense Health Board (DHB), to recommend how best to assess and prioritize leading value-based healthcare initiatives identified from private, public, and employer-based health plans. A., Glynn, N. W., King, A. C., Anton, S. D., Walkup, M., Lu, C., Reid, K., Spring, B., Pahor, M. METHODS FOR QUANTIFYING EFFICACY-EFFECTIVENESS GAP OF RANDOMIZED CONTROLLED TRIALS: EXAMPLES IN ARDS. Although lower baseline ABI was not associated with overall changes in cognitive function test scores, it was associated with higher odds for 2-year progression to a composite of either mild cognitive impairment or probable dementia (odds ratio 2.60 per unit lower ABI; 95% confidence interval 1.06-6.37). His books are on politics, primarily foreign affairs, and travel. Robert M. Kaplan is a Clinical Associate Professor, Graduate School Of Medicine at University of Wollongong. Expected final online publication date for the Annual Review of Public Health, Volume 43 is April 2022. The mean HVLT-R delayed recall scores were 7.22 for the physical activity group vs 7.25 for the health education group (mean difference, -0.03 words [95% CI, -0.29 to 0.24 words], P=.84). Each participant was categorized as having 0, 1 to 3, or 4 or more cumulative hospital days before each accelerometer assessment.RESULTS: Hospitalization increased sedentary time similarly in both intervention groups (8 min/d for 1-3 cumulative hospital days and 16 min/d for 4 cumulative hospital days). Bott, N. T., Sheckter, C. C., Yang, D., Peters, S., Brady, B., Plowman, S., Borson, S., Leff, B., Kaplan, R. M., Platchek, T., Milstein, A. He failed to recognize the innovativeness of man to overcome challenges. Physical activity interventions can slow the decline in quality of life, and targeting specific subgroups may enhance the effects of such interventions. Each minute per day spent being sedentary was associated with increased HCHD risk among both those with (0.04%, 95% CI 0.02% to 0.05%) and those without (0.03%, 95% CI 0.02% to 0.03%) CVD. OBJECTIVE: Incidence rates of ankylosing spondylitis (AS) among males versus females are poorly understood. Cost savings were measured as reduced spending by payers. The beneficial effect of physical activity on the incidence of MMD did not differ between frail and nonfrail participants.National Institute on Aging, National Institutes of Health. Bob has taken hundreds of jury trials to verdict, defending clients in premises liability, professional malpractice, products liability, assault, and motor vehicle liability cases. Using hospital discharge data for the period 2007-16, we compared acute myocardial infarction (AMI) hospitalization rates in San Diego County and the rest of the state before and after the demonstration project started. The November 2020 report, 'Modernization of the TRICARE Benefit', specifies a rubric to evaluate these value-based care initiatives not only in traditional measures of effectiveness but also in terms of the Defense Health Agency's Quadruple Aim with its focus on readiness. Obesity is an increasingly prevalent condition among older adults, yet relatively little is known about how built environment variables may be associated with obesity in older age groups. Implementing sobering centers as a treatment alternative for individuals with uncomplicated acute alcohol intoxication could yield substantial cost savings for the U.S. health care system. Intervention costs were estimated by tracking personnel activities and materials used for each intervention and multiplying by national unit cost averages. Philanthropist Mendel Kaplan dies, 73 - The Jerusalem Post Clinicians should consider targeted recommendation of physical activity and moderate-intensity exercise for older adults as a treatment to slow decline in eGFRCysC.Trial Registration: ClinicalTrials.gov Identifier: NCT01072500. Robert Joubert Expand search. Data from several sources suggest that this goal has never been realized. My wife, Jackie, and I were briefly in South Africa just last month, mainly to visit my 98-year-old mother who is barely hanging on in Knysna. DOCX Rsum - Stellenbosch University We performed a budget impact analysis from the perspective of the U.S. health care system based on published and gray literature reports. Robert Kaplan | The Jewish Agency This narrative review explores conceptual issues, and inconsistencies between evidence and opinion about screening.We examined the interpretation of screening studies in relation to three intellectual traditions: (1) The relationship between prevention and cure; (2) Confirmation bias and the challenge of incorporating new data: less care may produce better outcomes than more care; (3) The answers to three structured questions about efficacy, effectiveness, and value of treatments proposed by Sir Archie Cochrane and Sir Austin Bradford Hill.When considering extensions of life expectancy or all-cause mortality, systematic reviews typically show cancer screening to have only small effects and often non-significant effects on all-cause mortality.